Bayesian Quantile Impairment Threshold Benchmark Dose Estimation for Continuous Endpoints
نویسندگان
چکیده
منابع مشابه
Identification of a critical dose level for risk assessment: developments in benchmark dose analysis of continuous endpoints.
The benchmark dose (BMD) method has been recommended to replace the no-observed-adverse-effect-level (NOAEL) approach in health risk assessment of chemical substances. In the present article, developments in BMD analysis from continuous experimental data are proposed. The suggested approach defines the BMD as the dose at which the slope of the S-shaped dose-response relationship changes the mos...
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ژورنال
عنوان ژورنال: Risk Analysis
سال: 2017
ISSN: 0272-4332
DOI: 10.1111/risa.12762